Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A Estudos de biomonitoração do sistema urinário, circulatório
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چکیده
1 Tufts Center for Regenerative and Developmental Biology. Tufts University, Department of Biology, 200 Boston Ave. Suite 4600, Medford, MA 02155 USA. [email protected] 2 Institut für Klinische Pharmakologie und Toxikologie, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany 3 Division of Extramural Research and Training, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA 4 Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, USA 5 Laboratory of Environmental Toxicology, National School of Public Health, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil 6 Institute of Pharmacology and Toxicology, University of Wuerzburg, Wuerzburg, Germany Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A
منابع مشابه
Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A
BACKGROUND Bisphenol A (BPA) is one of the highest-volume chemicals produced worldwide, and human exposure to BPA is thought to be ubiquitous. Thus, there are concerns that the amount of BPA to which humans are exposed may cause adverse health effects. Importantly, results from a large number of biomonitoring studies are at odds with the results from two toxicokinetic studies. OBJECTIVE We ex...
متن کاملBiomonitoring Studies Should Be Used by Regulatory Agencies to Assess Human Exposure Levels and Safety of Bisphenol A
BACKGROUND Within the past 3 years, four major evaluations of bisphenol A (BPA) safety have been undertaken. However, these assessments have arrived at quite different conclusions regarding the safety of BPA at current human exposure levels. OBJECTIVES We compared the reasons provided by the European Food Safety Authority (EFSA) BPA risk assessment panel for their conclusion that human exposu...
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Objective(s): One of the major endocrine-disrupting chemicals, Bisphenol-S (BPS) has replaced bisphenol-A due to public health anxiety. The present study evaluated low dosage BPS effect on female reproductive potential, hormonal disruption, and gene expression pathways of blastocyst-derived cells.Materials and Methods: NMRI female mice (...
متن کاملOccurrence and Profiles of the Artificial Endocrine Disruptor Bisphenol A and Natural Endocrine Disruptor Phytoestrogens in Urine from Children in China
BACKGROUND Exposure to artificial or natural endocrine disruptors, such as bisphenol A (BPA) and phytoestrogens has been demonstrated to have health effects, especially in children. Biomonitoring of BPA and phytoestrogens in human urine can be used to assess the intake levels of these compounds. METHODS In this study, BPA and phytoestrogens in urine specimens (n = 256) collected from children...
متن کاملBiomonitoring Equivalents for bisphenol A (BPA).
Recent efforts worldwide have resulted in a growing database of measured concentrations of chemicals in blood and urine samples taken from the general population. However, few tools exist to assist in the interpretation of the measured values in a health risk context. Biomonitoring Equivalents (BEs) are defined as the concentration or range of concentrations of a chemical or its metabolite in a...
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تاریخ انتشار 2011